Yes. I calibrate the screen and reboot and the device no longer works. A new wrinkle is that I can't get the device to work most times now. Again, if I plug in the touch screen to my computer it's just fine. Using any of the USB ports on the DGE-2 results in no connectivity to the touch panel. Same USB cable. Occasionally I will return to the device and the touch will have begun working. I think this is an issue with the embedded windows elo driver. Do you know if there's any way to get to that? To update it??