Re: Should I upgrade to Y37- BIGY Y700 ?
What Iain is missing about long read technology is that there will be additionat STRs reported.? The current short read NGS technology is actually worse than the original Sanger technology in terms
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Wayne
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#8143
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Re: Should I upgrade to Y37- BIGY Y700 ?
I understand, thank you
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6458923@...
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#8142
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Re: Should I upgrade to Y37- BIGY Y700 ?
There are a lot of potentially iffy comparisons going on in the last few posts on this thread, so I think it's important to step back and think about what these numbers mean. I'm aware that many of
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Iain
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#8141
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Re: Should I upgrade to Y37- BIGY Y700 ?
Good question. Probably not a good answer: I wanted my parents WGS to put on a drive. I don¡¯t know what the future holds and it is a record I thought I would be glad I have one day. If not me, my
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Robert McMillan
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#8140
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Re: Should I upgrade to Y37- BIGY Y700 ?
Thank you for your comment I have two questions What were the benefits of testing your father? What were the advantages of two T2T WGS?
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6458923@...
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#8139
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Re: Should I upgrade to Y37- BIGY Y700 ?
I agree, my Dante test realigned to 60.3Mbp (from 23.6) My dad¡¯s Nebula test from 23.6 to 60.1M BP I have seen some Nebula results at or around 45mbp, and I think these come from Nebula realigning
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Robert McMillan
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#8138
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Re: Should I upgrade to Y37- BIGY Y700 ?
On Sat, Jun 22, 2024 at 08:30 PM, vineviz wrote: > > "WGS files from Nebula, when aligned to T2T almost never produce coverage > of more than 45 mbp." This sentence is completely wrong. ?My own
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6458923@...
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#8137
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Re: Should I upgrade to Y37- BIGY Y700 ?
WGS files from Nebula, when aligned to T2T almost never produce coverage of more than 45 mbp. ?And FTDNA files average closer to 30 mbp than 25. And that still doesn't mean that the difference (45 vs
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vineviz
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#8136
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Re: Should I upgrade to Y37- BIGY Y700 ?
WGSs, which offer short read, can currently call over 60 million bases. The BigY 700 is around 25 million, which is why I said it is insufficient. I think FTDNA will also offer a WGS test with short
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6458923@...
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#8135
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Re: Should I upgrade to Y37- BIGY Y700 ?
I don't think it is reasonable to suggest that Big Y is inadequate. For one thing, most of the 80 million bases are phylogenetically unhelpful. ?For this reason, full sequencing of the Y-chromosome -
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vineviz
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#8134
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Re: Should I upgrade to Y37- BIGY Y700 ?
The Big700 offers very inadequate coverage for the T2T reference, offering around 25 million bases. Human Ydna, on the other hand, can reach approximately 80 million bases, although this varies from
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6458923@...
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#8133
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Re: Should I upgrade to Y37- BIGY Y700 ?
FTDNA have said they will eventually re-align all Big Y 700 tests to so-called "T2T" reference genomes, and they've already done this for some kits. Vince
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vineviz
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#8132
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Re: Should I upgrade to Y37- BIGY Y700 ?
I will upgrade my test to Y111 in the next discount period.
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6458923@...
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#8131
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Re: Should I upgrade to Y37- BIGY Y700 ?
I applied a few days ago to set up a group project for R-Z49 at FTDNA.
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6458923@...
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#8130
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Re: Should I upgrade to Y37- BIGY Y700 ?
Thank you very much for your advice. I will upgrade to the Y111 test at the next sale. If FTDNA announces a new improved test that offers a new T2T ALIGNMENT then I will do that.
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6458923@...
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#8129
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Re: 2 matches in block tree but no big y matches
Thanks iain. I don't think theirs any benefit and my current y111 testers shared surname financially can't afford the upgrade and I said don't both as I believe we would all be the same anyway. For us
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jason jordan
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#8128
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Should I upgrade to Y37- BIGY Y700 ?
At Family Tree DNA, R-FT395781 is a six-person haplogroup and is about 2000 years old. I'll presume that you have looked at your results from YFull and found that you are FTA29830-, which limits the
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Iain
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#8127
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Re: 2 matches in block tree but no big y matches
Hi Jason, Should you spend the $99 to get the BAM file? That depends on what use you're going to make of it. First, let's understand the different classes of files. Put simply, FASTQ is the set of
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Iain
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#8126
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Re: Should I upgrade to Y37- BIGY Y700 ?
One of my Big Y matches (a ninth cousin by paper trail) doesn't match me at Y-37, so lack of matches at Y-37 doesn't necessarily mean a lack of matches at Big Y. Yahoo Mail: Search, Organize, Conquer
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[email protected]
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#8125
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Re: 2 matches in block tree but no big y matches
You need the BAM file.? It contains the "raw data" sequences.? The VCF file represents the analyzed results from the analysis pipeline.
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Wayne
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#8124
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