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CTS4466 Question 6
I'm adopted. I've discovered my birth mother, but she's passed and I can't narrow down my father. Thru Ancestry I can narrow down relatives, but i'm 99% sure most are from my father's mother. Through 23andMe I've found out my that haplogroup is CTS4466 and only two men that I'm related to share that with me and share 3rd great grandparents. Both are named Gilliam. My observations tell me that my "terminal" haplogroup might not actually be CTS4466. Does this sound correct? Thank you, Rick Smith
Started by rickwsmith@... @ · Most recent @
My Irish Type II tree 17
Thank you Lucas for intervening, I fully agree with your remarks. But David, I am not sure how you have derived the ‘From McCarthy tree’ allele values. If you track the STRs all the way from the block just below L21 at the top of sheet 2 down to FT43021 on sheet 11 – which I admit takes a bit of work! – you should find that by the time you reach 576: 18>19 (at the time of FT43021 itself), none of the others has changed. The tree construction is not automated in this respect so I will be more than happy to hear of apparent errors – I am sure there will be occasional ones - but they should be thoroughly checked out first. I do not have time to deal with a large number of what turn out to be spurious queries. I do though appreciate participants ensuring the validity of what they see, and letting me know about apparent errors*. They should first ensure they understand the Legend shown on Sheet 1. Combining STR analysis with the SNP data similar to that shown in FTDNA’s haplotree and its Block Tree views thereof, does result in a presentation packed with detail, but, as my ‘legacy’, since co-founding the project with Elizabeth ten years ago, I still believe it is best all presented in one place. * But first wait for the new update targeted for the end of this month! Kind regards = Nigel McCarthy Sent from Mail for Windows
Started by Nigel McCarthy @ · Most recent @
R-A7752 Moynihan and Mooney 8
We now have a Mooney sharing the same branch as Moynihan. The hope for this to happen was discussed in our post from October. Nigel, or anyone else, does the addition of Mr. Mooney give any further insight into this area of the Big Y Tree? Sue Minnehan
Started by Francis & Susan Minnehan @ · Most recent @
Ok
Started by Tom O'Hanlon @
Question for Nigel 3
Hi Nigel, regarding my previous question about Fran’s new Moynihan Y-700 match and your comments, is it ok if I screenshot your comments and share them with the wife of Mr. Moynihan who I’m communicating with? Also would it be ok if I shared page 24 of your tree which shows where these branches are located, as well as page 1 with your note #26. I’m also thinking of sending this information to Fran’s two Mooney Y-111 matches as maybe it would make them consider upgrading to Y-700. Would that be ok? I appreciate all your assistance. Best regards, Sue Minnehan
Started by Francis & Susan Minnehan @ · Most recent @
New Match on Big Y 18
Greetings all, in my never ending pursuit to try to figure out my husband’s Minihan/Moynihan ancestors, any comments and explanations about the following information will be greatly appreciated. in July a new Y-111 match with the surname of Moynihan posted with a genetic distance of 10 steps. Very soon thereafter an upgrade to Big Y was done. The results have posted and Mr. Moynihan has been assigned to haplogroup R-A7752. What is that telling us, if anything? Or just that his ancestors and my husband’s ancestors are so far back that it’s impossible to find the connection? Here’s a screenshot. Can anyone tell me what this means? Thanks all! Sue & Fran Minnehan
Started by Francis & Susan Minnehan @ · Most recent @
Irishorigenes etc 2
Hi Espen, Yes, I know of Dr Tyrone Bowes and his various Origenes websites (IrishOrigenes, ScottishOrigenes and EnglishOrigenes). I met Dr Bowes at the 2nd Genetic Genealogy Ireland Conference in Dublin in October 2014 where he described his methodology. I followed up with him during the following year about aspects of this. Whilst genetic genealogy has exploded over the past 10 years, Dr Bowes methodology was then (and to a large extent is still) based on the longstanding associations between surnames and geographical locations. Even back in 2015 I was arguing with him that this was not applicable in all instances - ' I have to disagree to a certain extent with you about surnames and locations. I agree that some names, and some branches of other names, can and do have long-term associations with a given location but others have clearly been subjected to dispersal pressures after surnames were adopted (the Great Famine being a recent example of a series of similar crises). And, no doubt, some people would have been subject to similar pressures before the adoption of surnames if they were unlucky enough to have been in the wrong place at the wrong time? And now traceable through SNP's?'. I now realise that many of these dispersal pressures also occurred before the adoption of hereditary surnames. In the case of the A151+ sub-branches of of CTS4466 / A541, I think that that Dr Bowes' methodology may lead to misleading results given that much of the further branching of this line occurred before the adoption of hereditary surnames in Ireland, Britain or Scandinavia and also given the wide geographical spread of this haplotype across Ireland, Britain and Scandinavia over a thousand years ago This is further compounded by the relatively small numbers of men identified thus far in these sub-branches. Dr Bowes certainly produces very visually striking case reports as illustrated in the case studies on his web sites but I would be doubtful that you would learn much more from him than from this group and your Big Y.. We would definitely learn more if we could identify and test more men who are A151+! All the best, John Brazil. On Tue, Aug 8, 2023 at 5:43 PM Espen Solheim <espheim@...> wrote: Hi Hope all is well! Have a question regarding Irish origenes (https://www.irishorigenes.com/content/re-writing-history). Anyone have any experience with the consultation and what can I as a Norwegian potentially learn that isn’t already known through this group and the DNA results from the big y itself? Espen Solheim/Johnsen
Started by john brazil @ · Most recent @
What ChatGPT Thinks of CTS4466 4
Hi Hope all is well! Have a question regarding Irish origenes (https://www.irishorigenes.com/content/re-writing-history). Anyone have any experience with the consultation and what can I as a Norwegian potentially learn that isn’t already known through this group and the DNA results from the big y itself? Espen Solheim/Johnsen
Started by Espen Solheim @ · Most recent @
Three Low Coverage R1b-S1121 PacBio Samples Received 5
The first batch of Dante Lab's HiFi Reads 3rd Generation WGS tests are in from the $900 launch last November. Here's the good: 1) Average read length 12,968 bases. 2) The HiFi reads are nearly as clean from noise as the Illumina short reads. Here's the bad: 1) The test appears to be designed to deliver between 10 and 15gb. Which equates to 3.4x coverage and about 1.7x for the Y chromosome. 2) The price of this test is now $1,900 which makes it very difficult to recommend to anyone. Especially, when it should really be at least 30gb. The B2B version of that test runs $3,800. I have a report page hosted here that lists the overall coverage on all the chromosomes in chm13 v2.0 and some calling metrics for WGS and Y DNA from my sample here, if anyone is interested. https://warehouse-public-resources.s3.us-east-2.amazonaws.com/GFX0457637/cov-analysis.html Comparing these is a bit more tricky since all literature suggests using DeepVariant as the caller instead of GATK. I'm not finding any off-the-shelf tools that will do joint genotyping, which is how I produce call matrices for building out trees. Any way... something to keep an eye out as the years go on and the price comes down. Revio is supposed to bring this down when the sequencers start to pay themselves off. James
Started by James Kane @ · Most recent @
Ciannachta...or not - origins of CTS4466 4
Hello, Michael and All. I’ve not commented on this thread yet, since I have a different point of view entirely. But I’ve decided to enter the conversation with another perspective, though it will mean a long-winded note to make my point. So… The question of where CTS4466 originated (or any other haplogroup, for that matter – M222, L226, etc.) will likely never be answered for certain, but the asking of it will certainly never cease. And James is correct that more – much more – aDNA is needed to have any realistic hope of narrowing down the possibilities with any certainty. Cassidy’s A Genomic Compendium of an Island contains the data for the two FGC11134 men that John referred to in a previous thread, along with a much later A151 sample on the east coast. There are advantages as well as disadvantages to her data, what we do have of it. Without the raw data, we can’t know if further downstream SNPs beneath FGC11134 were successfully tested negative or just no-calls. Getting results from ancient DNA is always much harder that modern samples. John and I have been trying with no success to obtain access to Cassidy’s raw data. A significant factor is that the dates she provided are not statistical estimates based on the DNA data but carbon dating from the associated artifacts found at the sites. No offense meant for the statisticians amongst us, but the old adage of there are ‘Lies, damned lies, and statistics’ is relevant here, since carbon dating, while not 100% accurate, is, I understand, much more reliable than statistical models of mutation rates. Of Cassidy’s two FGC11134 samples, she shows their ages as 2349-2135 BC and 2015-1758 BC . I’m not aware of Nigel dating FGC11134, but James’ tree shows 1967 BCE to 1776 BCE. Cassidy’s second date is slightly older, her first date is about 400 years older than James’ estimate. Now, looking at it as someone with no statistical training whatsoever but an inquiring mind, logically speaking, it seems difficult to feel any way comfortable that realistically, the ancient remains just happen to be anywhere near the time of the TMRCA of FGC11134. What this tells me, someone with no statistical training, is that however hard the statisticians have worked to get useful mutation rate models, the inevitable unknown factors in the mix make the mutation rates themselves at least somewhat unreliable, with the result that they underestimate the true ages of the SNPs. While CTS4466 – particularly S1121 – flourished in the south of Ireland, A7751, one of the earliest branches of CTS4466 on the tree, apparently split from CTS4466 itself within roughly around a few hundred years, much the same time as S1115 and subsequently ALL the rest of the downstream branches. And there is no question that the surnames in A7751 are mainly Welsh, with a few NI/Scots among them. Then just below S1115, brother to A212 (only in Northern Ireland, Scotland and England) is BY23591, also full of Welsh names. Now, while it’s quite possible that the Welsh names found in the A151 branch (with a much more recent TMRCA) are reverse migration, how likely is it that A7751 and S1115>BY23951 split from CTS4466 within a few hundred years/originated in the south of Ireland and migrated to establish themselves in Wales? A few A7751 have most recent ancestors in NI/Scotland. A212 is in NI/Scotland/England. Isn’t it far more likely that CTS4466 itself originated in Wales, and the early migrations of CTS4466 folk travelled north from Wales, across the Irish Sea from Scotland, where on a clear day you could see Ireland, some stopping in the North (A212), the rest travelling south, some more stopping in Leinster (A663), and some going the whole way to Munster and flourishing big time there? I too have tried to meld the annalistic/historical/mythical/folklore details from Irish origin myths with the DNA data we have, but accepting that at least some of it is pure fabrication – even from historical times (eg the Dál Cais claiming ancestry from Eoghan Mór’s brother to elevate themselves and justify their usurpation of the Eóganacht hegem
Started by Elizabeth @ · Most recent @
Ciannachta 4
Hello! This group has a lot of members well versed in Irish history, so I was hoping someone may recognize the reference here about the Ciannachta that "The Ciannachta groups were absorbed over time." https://en.wikipedia.org/wiki/Ciannachta It is unfortunately not cited. I ask because the Ciannachta are not a bad candidate for A212s- Munster origin, supposed kin to the Eoghanachta, moving to Meath and into Ulster. The Ely O'Carroll have a claim to Ciannachta origins and are DF21, so it is not a perfect alignment. The native Irish surnames under A212 have a variety of tribal origins and could fit the "absorbed over time" well.
Started by Michael Adams @ · Most recent @
What ChatGPT Thinks of CTS4466 50
In case anyone is curious about ChatGPT's "thoughts" on the origins of CTS4466: Prompt: Where did R1b-CTS4466 originate? Response: > R1b-CTS4466 is a subclade of the R1b haplogroup, which is one of the most common Y-chromosome haplogroups among males in Western Europe. The R1b haplogroup is believed to have originated in the Near East or Southwest Asia, and it spread to Europe during the Neolithic period, around 8,000 years ago, with the arrival of farming. > > The R1b-CTS4466 subclade is a more recent branch of R1b and is estimated to have emerged approximately 4,000-4,500 years ago. While the exact origins of R1b-CTS4466 are not entirely clear, it appears to be associated with the spread of the Bell Beaker culture in Western Europe during the Bronze Age. > > The Bell Beaker culture is believed to have originated in the Iberian Peninsula and spread throughout much of Western Europe between 2800-1800 BCE. The Bell Beaker people are known for their distinctive pottery and their use of metalworking technology, such as bronze and copper, as well as for their burial customs. > > Genetic studies have found that R1b-CTS4466 is particularly common in Western Europe, including in the British Isles, the Iberian Peninsula, and France, which are regions that were heavily influenced by the Bell Beaker culture. This suggests that R1b-CTS4466 may have been spread by the Bell Beaker people as they migrated throughout Europe during the Bronze Age. However, additional research is needed to confirm this hypothesis. Here it’s obviously referencing the Bell Beaker papers and seems unaware of new publications. So not too terrible and on par with what 23andMe would tell a tester based on their chip panel. Asking for examples of famous individuals... it seems to straight be making things up. The locations and people aren’t just implausible but are impossible in some cases. Response: > It's not possible to determine the Y-chromosome haplogroup of historical figures without direct genetic testing, so we cannot definitively say who some famous R1b-CTS4466 men were. However, based on the prevalence of the R1b-CTS4466 subclade in certain populations, it is possible that some historical figures were carriers of this haplogroup. > > For example, R1b-CTS4466 is relatively common in the British Isles, where it is estimated to be present in about 8% of the male population. Some famous historical figures who were likely of British or Irish descent and could have carried this haplogroup include King Arthur, William the Conqueror, and St. Patrick. > > R1b-CTS4466 is also found at high frequencies in the Basque Country, which is an area in Northern Spain and Southwest France. Some famous Basque people who could have carried this haplogroup include the explorer Juan Sebastián Elcano and the philosopher Miguel de Unamuno. > > It's important to note that while certain haplogroups may be more common in certain populations, it is not possible to determine a person's ancestry or ethnicity based solely on their haplogroup. Haplogroups are just one piece of genetic information and do not provide a complete picture of a person's genetic heritage. The tool is interesting for sure but has a long way to go before it’s actually useful, especially since it doesn’t provide references for its assertions. If anyone would like to see something else from the bot and doesn’t have an account of their own let me know. James Kane
Started by James Kane @ · Most recent @
BY201782: Kissane Branch? 12
We had an O’Casson kit (B715767) do big Y and get placed as BY201782, which Nigel has with dates for a MRCA of 1150 AD (if I’m reading that correctly). What may not be readily apparent is that the Cashman kit (539013) who placed at BY201596 is an equivalent surname (also equivalent to Kissane). So we have two Kissane/Cashman/Casson surnames popping up under BY201782, which is recent enough to be a surname branch. The only others under that are the two Sheehans, which are me and my distant cousin that have a paper trail back to a MRCA born 1774. So I think we may be on the cusp of defining the “real” Kissane/Cashman/Casson cluster, which would mean me and my cousin are actually genetic Kissanes. I think I need to try to get Kissane Kits 232067 and 259030 to do further testing: they’re already under BY2880, which is the right beginning; if we find they’re also placing under BY201782, and there isn’t some other defined cluster somewhere, then I think we could safely conclude it’s the “actual” Kissane genetic signature. Nigel, does that sound right?
Started by Dustin Shane @ · Most recent @
BY201782: Sheehan Branch?
Z38201 for Sheehan Big Y match; 17th century SNP.
Started by EdSmith’49 @
PacBio's New Revio Long Read Sequencer
In October 2022, PacBio announced the Revio System. This is capable of delivering HiFi reads with lengths of 15000-18000 bases for under $1000 with 30x coverage depth on a human-sized genome. These are the same types of reads we see used in the PanGenome ( https://humanpangenome.org ) related projects to assemble the gapless references such as CHM13. From the product sheet it also looks like the call accuracy for variant callingis quite similar to the much shorter 150 base reads in Illumina NovaSeq like with Big Y 700. The platform looks to be coming soon from Dante Labs, which as everyone should be aware has lead the market with getting prices down on WGS but also has notorious history with actually delivering in a timely fashion. I have one on order and will share my experiences. Best case scenario is that we will wind up with a gapless S1121 Y chromosome to use as a reference going forward. Worst case... I wind up with more garbage like the Oxford Nanopore Test they botched for me in 2019 and spending another 6 months getting a refund. Edit: Forgot to link the PacBio product page ( https://www.pacb.com/revio/ ). James
Started by James Kane @
DYS612u5 2
Looking at the type 2 tree i see the branch from FT43021 down to A1133 shows 576 18>19 385b 15>16 612u5 27>28 561 15>16 FTY191 11>10 would every person that is part of A1133 have these mutations?
Started by David Delacy @ · Most recent @
Irish Type II 3
Hi Nigel, I thought I was done pestering you but its seems I was premature, a cousin - Thomas H Miller - tested and his results have moved my son and I, on from R-FTB71099, on to a newly formed haplogroup R-FTB72303. Nigel, as James Millar (Kit no: SI14537) and me (Kit no: B654981) have reviously given you our permission to publish our info, you won't require a further permission? Nigel, I'll inform Thomas H, if he wants to add to your tree, he'll need to fire you off his details and his permission to publish. Nigel, have a Merry Christmas and a Happy New Year - thank you for all the hard work, you do for us CTS4466ers. Nollaig Shona dhuit agus adh mor ort! Phil From: [email protected] <[email protected]> on behalf of Nigel McCarthy <ndmccarthy10@...> Sent: Monday, 24 October 2022 12:52 AM To: [email protected] <[email protected]> Subject: [R1b-CTS4466-Plus] Irish Type II tree: 23 October 22 update I have just published an update of my Irish Type II tree and its associated Mutation Block Age Table. As usual, these will be found on the McCarthy Surname Study Scrapbook site at https://mccarthydna.wordpress.com/. (Please do not attempt to join this study though, unless you are a male McCarthy). The number of Big Y-700 tests contributing to the age computation now stands at 474, i.e 44 added since the 30 Sep 22 issue. The following sheets ONLY have been updated in this 23 October issue: 1-3 5-8 12, 13 15-17 The next update (it is hoped by end of November) will focus on outstanding contributions on Sheets 4, 14, and 18-21. I am generally only adding / updating kits which have tested to Big Y-700. Kind regards = Nigel McCarthy
Started by Phil Millar @ · Most recent @
Irish Type II tree: 23 October 22 update 4
I have just published an update of my Irish Type II tree and its associated Mutation Block Age Table. As usual, these will be found on the McCarthy Surname Study Scrapbook site at https://mccarthydna.wordpress.com/. (Please do not attempt to join this study though, unless you are a male McCarthy). The number of Big Y-700 tests contributing to the age computation now stands at 474, i.e 44 added since the 30 Sep 22 issue. The following sheets ONLY have been updated in this 23 October issue: 1-3 5-8 12, 13 15-17 The next update (it is hoped by end of November) will focus on outstanding contributions on Sheets 4, 14, and 18-21. I am generally only adding / updating kits which have tested to Big Y-700. Kind regards = Nigel McCarthy
Started by Nigel McCarthy @ · Most recent @
tree mappings variance? 5
Something i'm noticing with the irish type II tree. Hoping someone can help it make sense If i look on FTDNA at someone that is tested as R-BY39363 It shows i am 5 Genetic steps away from them and 4 genetic steps away from R-FT95639 to me this seems to suggest i'm in the wrong location of the tree or R-FT95639 might not have branched from R-BY39363 or some sort of other mutation problem lol anyways, tell how wrong i am since i dont know thanks!! Me> R-FT43021 (delacy) 1185 A.D.? 5 steps away from R-BY39363 1330 A.D.? 4 steps away from R-FT95639 1355 A.D. ? Thanks Dave
Started by David Delacy @ · Most recent @
Irish Type II Tree 2
Hi Nigel You might be interested in the date 1838 – date of common ancestor of Peter Ryan and I. I was communicating with Paul O’Donnell who said I should give you the date of my common ancestor with Peter Ryan. Common Ancestor John Ryan b1838 Yass NSW His father just for interest was Patrick Ryan b1811 (married in Kilrush Clare) and his father Timothy Ryan b Timothy b1778 (presumably Kilrush). So 1778 is about the right age for us to branch off from John Ready. Plus or minus 150 years. Patrich Ryan leased land at Moyodda Beg just outside Kilrush – We believe he leased land there in 1826 – although only 14 years old – as it was nearby to his future wifes family and father in law as well. This is John Ryan in Warrnambool. On another topic I am trying to go up the learning curve on all this Big Y stuff. As my Big Y and Peter Ryan’s FTDNA upgrade to Big Y are recent I believe I need to pay the $100 for the Y700 BAM file if we wish to go on to James Warehouse. Matt Ryan B475646 Peter Ryan 535083 Matt Ryan
Started by Matt Ryan @ · Most recent @
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