You may be trying to connect to the default ref.d-rats.com rsatflector which is no longer in use. Check for a list of working ratflectors at dstarinfo.com.
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If you are running OneDrive, read the instructions on dstarinfo.com for D-RATS. One drive “hijacks” the Desktop folder to a different location under c:\Users.? The instructions will correct the issue with the error during first time setup.