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Telomere? Centromere?
Hi, all! In follow up to my question about determining the location of a SNP on the Y chromosome, I've been poking around Y Browse (thank you, again, for pointing me to this).? My question now is -
By mlh · #7964 ·
Re: Find location of SNP
Wow!? Lots for me to absorb, Vince!? Thank you so much for providing the links to the detail on the Y chromosome centromere.? This helps me visualize the issues with mapping in the centromere and
By mlh · #7963 ·
Re: Find location of SNP
HI Mary, Ybrowse.org lists the various cytobands for the Y-chromosome here: https://ybrowse.org/gbrowse2/gff/cytobands_hg38.gff3 Specifically for the centromere, build hg38 index range
By vince@... · #7962 ·
Re: Find location of SNP
Thank you for the information you shared, Brian!? I knew the PAR regions of the X and Y chromosomes can undergo recombination but didn't realize the centromeres of a male's X and Y could also
By mlh · #7961 ·
23andMe Raw DNA Data Download Instructions
FYI: Update from 23andMe DNA: Anyone with files from this company can once again download their DNA with NEW
By Dan D. · #7960 ·
Re: Find location of SNP
Hi Mary I think this makes sense. We are talking about different domains of the Y-Chromosome. The PAR regions are at the ends of the X- and Y-Chromosomes, whereas as its name suggests the centromere
By Brian Swann · #7959 ·
Re: Find location of SNP
Thank you for your explanation, Iain, and the link to the Nature article! From your explanation, it sounds like the issue is extremely long STRs in the Y chromosome centromere, rather than "cross
By mlh · #7958 ·
Re: Find location of SNP
Hi Mary, Yes, that's right. Since men get an X from their mother and a Y from their father, and since (outside the PAR regions) they don't recombine, the centromere is still part of the male-specific
By Iain · #7957 ·
Re: Find location of SNP
Hi, all! Thank you, Brian and Vince, for additional information on this question.? I'm enjoying the additional discussion. One of the reasons I asked the question was because of this response from
By mlh · #7956 ·
Re: Find location of SNP
Hi Vince, All Your comment here has sent me down a bit of a rabbit hole, Vince - but quite an interesting rabbit hole. Let me check first - I am assuming your sentence "Because of this Y-SNPS found in
By Brian Swann · #7955 ·
Re: Find location of SNP
The only quibble I have with the diagram of the Y chromosome in Iain's outdated primer is that he illustrates the Y-chromosome as a diploid chromatid (
By vince@... · #7954 ·
Re: Find location of SNP
Thank you, Rachel and Iain, for pointing me to YBrowse - perfect.? And thank you, too, Iain, for the link to your U106 Explored paper.? The diagram on the last page is very helpful - and I think
By mlh · #7953 ·
Re: Find location of SNP
Hi Mary, If you have a name, you can look up the corresponding position on the Y chromosome on YBrowse.org (or vice versa). Simply enter the name in the search box and its context will appear. Click
By Iain · #7952 ·
Re: Find location of SNP
Ybrowse.org
By Rachel Unkefer · #7951 ·
Find location of SNP
Hi, all! What is a good resource for determining where on the Y chromosome a particular SNP is, please? Do you start by finding the position number of the SNP by using the FTDNA chromosome browser??
By mlh · #7950 ·
Re: Question about the location of my clade (a downstream clade to R-FGC12988)
Well Skinner is an occupational surname so it is difficult to say when or why your ancestor ended up in Tralee.??Elizabeth I in 1587 granted Tralee to Sir Edward Denny
By A321son <bpkgroups@...> · #7949 ·
Re: Question about the location of my clade (a downstream clade to R-FGC12988)
Hi Saul, Go into website: www.irishgenealogy.ie ( http://www.irishgenealogy.ie ) Click Church records You will find? several entries for Skinners from Tralee around 1800. Kevin -- Kevin Terry
By Kevin Terry · #7948 ·
Re: Question about the location of my clade (a downstream clade to R-FGC12988)
Hello Saul Probably not much help, but one Skinner man is listed here | Surname | First Name | Parish/Barony | County | | Following are the exact matches: | | Skinner | John | Keady | Armagh |
By John T · #7947 ·
Re: Question about the location of my clade (a downstream clade to R-FGC12988)
Good idea, So far all I know is that our last name is Skinner, and the earliest ancestor I can find is a John Skinner from around 1837.
By Saul · #7946 ·
Re: Question about the location of my clade (a downstream clade to R-FGC12988)
Hi, My last name is Skinner, and the earliest known ancestor I know is a John Skinner around 1837 I believe, and then the Irish genealogy records stop for him. There is a singular document which seems
By Saul · #7945 ·