Re: Y111 STR counts for U106
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Way back in ancient DNA times DYF371X results did appear to support some branching under Z326.? Overlaying DYF371X results on top of the current branch structure would be an interesting exercise.? I also wonder if in some of the well tested lines such as Cecil if relevant DYS371X branching is observed.? I have not done DYF371X across my broad paternal line. Wayne
On Monday, July 1, 2024 at 12:51:05 PM EDT, Myles Twete <matwete@...> wrote:
Thanks Martin. And I¡¯m glad you included the ZERO counts.? On my leg of U106, we our all DYS425=0, which evidently formed about 1500BCE with Z326 haplogroup. But that ZERO itself doesn¡¯t tell the actual story (at least as regards DYS425).? I tested my father¡¯s sample at YSEQ for DYF371X (DYS425 is a subset) and it appears that my father and I are DYS425=10c Our sample: DYF371X 10c-10c-13c-14c Most common DYF371 haplotype in R1b is 10c-12t-13c-14c You see, Y67/111/etc. DYS425 only reports a STR count if the repeats are type ¡°T¡± --- if instead it flipped to ¡°C¡± at some point, the test does not read or report it. Of the 297 ¡°Zero¡± samples for DYS425 in the database, I¡¯d guess that most or all of them have repeats that are ¡°12c¡±, ¡°11c¡± or ¡°10c¡±. We are currently testing 3 more samples in our tree for DYF371X---one with MRCA at about 500ybp, another at perhaps 1000ybp and another at about 1500ybp. Since we see a few DYS425=12 in our Project (Cecil-Cessill), I suspect that the change that happened around Z326 simply flipped from 12t to 12c, then over time on our part of the tree mutated further to 11c, then 10c.? Or maybe some other scenarios¡ ? If any of you are also under Z326 and see a DYS425=0, you might also consider testing for DYF371X. There are 10x more DYS425=0 than any other result except CYS425=12, which is about 16x the number who have zero as the result. For sure, the STR difference counts reported for sample comparisons under Z326 are ignoring any mutations at DYS425 unless they backmutate to ¡°t¡±. This means that while we might think we have a GD:1 match at Y67 with someone, the actual number could be GD:2, it¡¯s just that that second one is masked by this ZERO. Not all zeroes are the same¡ ? Thanks! ? -Myles ? ? From: [email protected] [mailto:[email protected]] On Behalf Of Martin Abrams via groups.io ? I needed a project to re-teach myself Excel.? ?I used to be pretty good at Excel but that was 15 years ago and I have not really touched it for the last 10 years.
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Wayne