I don't know exactly why, but when I've had issues getting rig control to work on MacOS or Linux I've found that FLRIG is more forgiving.??
Try setting up FLRIG to control it and then set WSJT-X to work with FLRIG.
Also from experience, I've learned that I need to reboot between settings changes when things don't work on some systems.? It seems to lock up the I/O in some cases. In those cases port failure can be mistaken for wrong settings.
--Neil, W2NDG
Neil Goldstein