I have TK4- running on a PI Zero. ?Slow to install. ?Even TSO works!
I also have a PI4B with 4GB of memory running TK4- among other things. ?
Buy the new 8GB of the PI4 ?and you should able to run several programs at once.
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Regards,
Bernie (did 360 assembler programming on large ?IBM Model 75 in late 1960s)