So I've plugged in the USB 2.0 hub and nothing has changed. I have removed all devices aside from the new hub and the SA.
Even weirder is this:

There are no other entries for the SA in the device manager.
The tinySA-App reports this when trying to connect to the DFU.
?
Loading "C:\Users\jpiro\Downloads\Electronics Projects\Tinysa\tinySA_v1.4-120-g6c349b9.dfu" ..
112829 bytes loaded OK from C:\Users\jpiro\Downloads\Electronics Projects\Tinysa\tinySA_v1.4-120-g6c349b9.dfu
DFU element address [0]: 0x08000000
DFU element size [0]:? ? 112520
Firmware size: 112520 bytes
Opening \\?\usb#vid_0483&pid_df11#fffffffeffff#{a5dcbf10-6530-11d2-901f-00c04fb951ed}?
?open failed?
No valid DFU device found
Have you put your NanoVNA into DFU mode ?