Hello Rune,
Thank you very much for the nanoVNA program.
It is a prosmising start.
It works also under MacOS Mojave 10.14.6, see the attached screen shot.
You just have to edit: self.serialPort = "/dev/cu.usbmodem4001" in program NanoVNASaver.py
I use Python version 3.6.3.
The only deviation from your screen shot is the data representation.
In your screen shot it is a line, in mine there are dots only.
73, Rudi DL5FA