Gord -
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I was having an identical problem to what you describe about "Setting" cars a week or so ago.
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It turned out it was a conflict between what I wanted to do, and what either the "route" for the car, or the "location" of the car, was set at and permitted me to do.? I fixed my issue by going to either the 'route' or the 'location', and changed the "train direction" settings.? I don't remember exactly, but I think it was the Location, using the "Edit Location" button.
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Clarence