Clear thin (both width and thickness) strip of plastic.??
Scrap bit of PCB at each end, pulled taught and affixed to drill bed.??
Put a scrap PCB underneath and drill through, mark around hole for easier sighting,? now put your pcb to be drilled under there and use that to align.
Ogviously the plastic strip needs to be long enough that you have sufficient ability to locate the PCB under the hole for all holes required.
Picture for clarity.
? ?
As others have said, those cross hair laser things are not made for such small and precise holes.? Camera and/or mirrors better for removing any parallax error (or rather making it consistently compensated for).
