Tech support told me to roll back to SIMPL?4.11.06 because of issues I was having compiling. Apparently newer SIMPL is only meant for programming 4-series at the moment.
Newer versions of SIMPL gave me compiler warnings about Cisco modules and the sandbox, and some old Biamp modules stopped working properly. The Biamp modules would appear to compile properly, but the "Is Communicating" signal failed to ever go high.