Yes, you can use larger boosters.?
One thing to keep in mind is that if you are going to use common ground boosters, then you won't want to use the command station as a booster since it is opto isolated.?
Another option, which is how I chose to go, is to use multiple smaller boosters and break the layout up into power districts. My doing this, I am able to retain RailCom and have eliminated the need for circuit breakers.
Ryan
Iron Planet Hobbies