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Re: Supplements exposed :filling materials of pharmaceuticals


taray singh
 

Hi guys
Pharmaceuticals have some active ingredients but their main components? are fillers.
These? fillers have some functions which? are not? necessarily therapeutic but can influence the tolerance to a drug.
But they can be? ?used for identification of manipulated products? such as presence? of inorganic compounds? especially in some generics.
As a reference I have provided a micro xrf lab results of a sample of Aspirin Baeyer original and a generic.
The generic filler has more inorganic compounds? compared to the original
Pb is astonishingly present in the generic
Unfortunately Pb residual peaks makes it difficult to make an? analysis regarding the presence of lead with Am setup
Here I am using generic form of clopidogrel a common antiplatelet medication? better? known as Plavix
My sample is a few tablets in a polyethylene? container.
Ideally should be ground to a flat sheet for xrf
Anyway my xrf show peaks of Ti? and? Fe like the lab results
Best stay away from generics for long term usage drugs
Taray

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