Thank you for the reply. I am using a USB 3.0 M.2 NVME adapter. It plugs into the USB port on the Pi4. It will not boot. It see's the USB drive but, will not start the boot process. I can take a screen shot later and post the errors

I am getting. I have the Pi4 set to USB boot first, and flash card second (no flash card installed). Still nothing. Do I have to flash the EEPROM to get this to work? Thanks.