How much do you need to backup?? Specific content and you'd just reinstall, or do you want to be able to do a bare metal recovery it stops booting from the SSD?? Simplest is do a full disk duplication (dd) of the SSD.? You'll have to do this with it UNMOUNTED, which means boot pi from another device, or power down, connect the SSD to another system and run dd from there.? If you want to save specific folders and directories, an rsync script or one of the suggestions in the thread will do.? I'd include /boot (capture boot-specific options), /etc (lots of config files), /home and /usr.?
What I'd consider is do a full image periodically by whichever means you prefer.? More frequent incremental backups of directories where you are adding content you do not want to lose.? The incrementals can be run as file or rsync copies from a live system, so the only interruptions are disk and maybe network access if you are backing up to storage on another system.? I'd also backup a basic bootable system to an SDcard and keep it handy just in case.
73 Steve KS1G