Will you have an override facility which can be applied if you are in agreement with me (if ever you have time to review such cases in depth!)?
Yes, eventually. ?I am on and off working on a set of editing tools for the tree. ?Each branching block notes the changes from its parent block. ?The state changes can be SNPs, INDELs or STRs. ? ?Way down the road I¡¯d also like to include a concept like a person as well for proven lineages. ?The state changes can be redefined manually in the report that renders the tree in your browser.
The intent is to allow a team to fix the tree¡¯s mistakes and make further refinements manually.
Will the Warehouse trees have similar characteristics, or will STR mutations only be marked as coincident with SNPs?
Yes, covered by the above functionality. ?A new Block with the STR mutation could be inserted between existing SNP block. ?I already do this with INDELs , since including them is an NP-hard problem for the current machine learning solutions.
Thanks,
James
