I have a Multiprise 3000 system and, now, lots of spare disk space. It struck me a few moments ago that I can now run MTS on it. The system currently runs VM/ESA 2.4, z/OS 1.5, VSE/ESA 2.4, and MVS/XA 2.2.3, all snappily enough for a small number of users.
Will MTS use VM for anything beyond a simple hypervisor? MUSIC/SP does, since it needs the VM IUCV to talk to the VM TCP/IP stack, but I don't recall what considerations there are for MTS.