+ AA6YQ comments below
I'll Reboot Windows into "Safe Mode with Networking", then start DXKeeper.....and report results.
BTW With DXview not selected, DXkeeper Lookups are instantaneous. (Is that a clue, or that's how it's supposed to be?)
+ That's a clue that "something" on your system is slowing the performance of communication between applications.
73,
Dave, AA6YQ