I had a similar experiance to you, Brian, but in my case the issue was a Configear port adapter (USB/HDMI/Audio/Ethernet hub). My X6100 USB Dev port worked fine connected directly into my Windows 10 desktop using the same USBC => USBC => USBA adapter I have been using for my QRP Labs QMX on my HP Laptop via the Configear port adapter on the laptop. However, that did NOT work with the X6100 via the same Configear hub I used for my QMX. I had to connect directly to the laptop, either via the same USB C => USB C => USB A adapter I use for my QMX or via the original X6100 Cable USB C => USB A => USB C adapter into the laptop's USB C port (which is preferable because I use the USB A port on the laptop for a mouse bluetooth plug).
cube1us