490-1208-ND is a 4MHz ceramic resonator. For clock accuracy its pure crap. That parts has 0.5% accuracy. That's 5000ppm, or ~7minutes / day off. A regular crystal has accuracy of 30ppm, or ~15minutes / year (~3 seconds / day). Amazingly, the US and Western Europe, have AC line frequency, that if used, will keep your clock ON time, within a minute, per year (2ppm).
Muxing is commonly used for displays, including nixies. Nixies do have a finite turn-ON time. They don't turn ON instantly. Typically, its in the range of 10's of microseconds. As for muxing frequency, try a complete set faster than 60Hz, to avoid flicker. That is: Dig-1 On for 2.5mS (milliseconds, or 2500microseconds), then blank (all digits off) for 200uS (microseconds), dig-2 on for 2.5, blank (200uS), and so on, for all 6 digits for (2.5+0.2)=2.7mS*6=16.2mS (or 61.7Hz). During those blanking intervals is when you switch the digit data going to your ONE (common) 74141.