Chris I just connected my Digirig to my IC-7000 via the 6 Pin DIN plug and it keyed up the radio just fine while using VARA HF. I monitored the audio on my HT and the audio was transmitted as well.
I do not have the CAT cable for the IC-7000 so I had to specify the com port in the optional transmitting section of the VARA setup. In my case it was COM10.
Sorry I could not help any more, but hopefully you get it going.
73
John Denison
KD5YOU